Common Pathway (Last Updated - 2/27/2005)

-involves Factors X, Xa, V, Va, II (Prothrombin), IIa (Thrombin), I (Fibrinogen), Ia (Fibrin), XIII & XIIIa
-a deficiency of any of the above factors will lead to prolongation of both the PT & aPTT
-click here to view an image of the clotting cascade

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References:

Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.